Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'TRAF2 and NCK-interacting protein kinase' and Ligand = 'BDBM174021'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
TRAF2 and NCK-interacting protein kinase (Homo sapiens (Human))	BDBM174021 (US9102637, 56) Show SMILES CN1CCN(Cc2cc(cs2)C(=O)Nc2sc(Nc3cccc4ncccc34)nc2C(N)=O)CC1 Show InChI InChI=1S/C24H25N7O2S2/c1-30-8-10-31(11-9-30)13-16-12-15(14-34-16)22(33)29-23-20(21(25)32)28-24(35-23)27-19-6-2-5-18-17(19)4-3-7-26-18/h2-7,12,14H,8-11,13H2,1H3,(H2,25,32)(H,27,28)(H,29,33)	PDB UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	8.20	n/a	n/a	n/a	n/a	7.5	25
CARNA BIOSCIENCES, INC.; NATIONAL CANCER CENTER US Patent					Assay Description The kinase assays were conducted in a 20 μl volume using 384-well plates (Greiner). The reaction mixture consists of compound or vehicle (1% DMS...				US Patent US9102637 (2015) BindingDB Entry DOI: 10.7270/Q2KS6Q9T
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