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Found 1 hit Enz. Inhib. hit(s) with Target = 'TRAF2 and NCK-interacting protein kinase' and Ligand = 'BDBM174093'   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kJ/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
TRAF2 and NCK-interacting protein kinase


(Homo sapiens (Human))
BDBM174093
PNG
(US9102637, 128)
Show SMILES [#6]\[#6](-[#6])=[#6]\[#6](=O)-[#7]-c1sc(-[#7]-c2ccc3ccc(F)cc3c2)nc1-[#6](-[#7])=O
Show InChI InChI=1S/C19H17FN4O2S/c1-10(2)7-15(25)23-18-16(17(21)26)24-19(27-18)22-14-6-4-11-3-5-13(20)8-12(11)9-14/h3-9H,1-2H3,(H2,21,26)(H,22,24)(H,23,25)
PDB

UniProtKB/SwissProt

B.MOAD
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem

Similars

US Patent
n/an/a 7.20n/an/an/an/a7.525



CARNA BIOSCIENCES, INC.; NATIONAL CANCER CENTER

US Patent


Assay Description
The kinase assays were conducted in a 20 μl volume using 384-well plates (Greiner). The reaction mixture consists of compound or vehicle (1% DMS...


US Patent US9102637 (2015)


BindingDB Entry DOI: 10.7270/Q2KS6Q9T
More data for this
Ligand-Target Pair