Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'TRAF2 and NCK-interacting protein kinase' and Ligand = 'BDBM174128'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
TRAF2 and NCK-interacting protein kinase (Homo sapiens (Human))	BDBM174128 (US9102637, 163) Show SMILES NC(=O)c1nc(Nc2ccc3ccccc3c2)sc1NC(=O)c1ccc(CNCCO)cc1 Show InChI InChI=1S/C24H23N5O3S/c25-21(31)20-23(29-22(32)17-7-5-15(6-8-17)14-26-11-12-30)33-24(28-20)27-19-10-9-16-3-1-2-4-18(16)13-19/h1-10,13,26,30H,11-12,14H2,(H2,25,31)(H,27,28)(H,29,32)	PDB UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	3.70	n/a	n/a	n/a	n/a	7.5	25
CARNA BIOSCIENCES, INC.; NATIONAL CANCER CENTER US Patent					Assay Description The kinase assays were conducted in a 20 μl volume using 384-well plates (Greiner). The reaction mixture consists of compound or vehicle (1% DMS...				US Patent US9102637 (2015) BindingDB Entry DOI: 10.7270/Q2KS6Q9T
					More data for this Ligand-Target Pair