Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'TRAF2 and NCK-interacting protein kinase' and Ligand = 'BDBM174138'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
TRAF2 and NCK-interacting protein kinase (Homo sapiens (Human))	BDBM174138 (US9102637, 173) Show SMILES NC(=O)c1nc(Nc2ccc3ccccc3c2)sc1NC(=O)c1ccc(CN2CCC(O)CC2)cc1 Show InChI InChI=1S/C27H27N5O3S/c28-24(34)23-26(36-27(30-23)29-21-10-9-18-3-1-2-4-20(18)15-21)31-25(35)19-7-5-17(6-8-19)16-32-13-11-22(33)12-14-32/h1-10,15,22,33H,11-14,16H2,(H2,28,34)(H,29,30)(H,31,35)	PDB UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	3.40	n/a	n/a	n/a	n/a	7.5	25
CARNA BIOSCIENCES, INC.; NATIONAL CANCER CENTER US Patent					Assay Description The kinase assays were conducted in a 20 μl volume using 384-well plates (Greiner). The reaction mixture consists of compound or vehicle (1% DMS...				US Patent US9102637 (2015) BindingDB Entry DOI: 10.7270/Q2KS6Q9T
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