Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'TRAF2 and NCK-interacting protein kinase' and Ligand = 'BDBM174154'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
TRAF2 and NCK-interacting protein kinase (Homo sapiens (Human))	BDBM174154 (US9102637, 189) Show SMILES NC(=O)c1nc(Nc2ccc3ccccc3c2)sc1NC(=O)c1ccc(CN2CCCCC2CO)cc1 Show InChI InChI=1S/C28H29N5O3S/c29-25(35)24-27(37-28(31-24)30-22-13-12-19-5-1-2-6-21(19)15-22)32-26(36)20-10-8-18(9-11-20)16-33-14-4-3-7-23(33)17-34/h1-2,5-6,8-13,15,23,34H,3-4,7,14,16-17H2,(H2,29,35)(H,30,31)(H,32,36)	PDB UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	6.80	n/a	n/a	n/a	n/a	7.5	25
CARNA BIOSCIENCES, INC.; NATIONAL CANCER CENTER US Patent					Assay Description The kinase assays were conducted in a 20 μl volume using 384-well plates (Greiner). The reaction mixture consists of compound or vehicle (1% DMS...				US Patent US9102637 (2015) BindingDB Entry DOI: 10.7270/Q2KS6Q9T
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