Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Target of rapamycin complex 2 subunit MAPKAP1' and Ligand = 'BDBM50505422'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Target of rapamycin complex 2 subunit MAPKAP1 (Homo sapiens)	BDBM50505422 (CHEMBL4562100) Show SMILES [H][C@]12Cc3c(nc(nc3N3CCOCC3(C)C)-c3ccc(N)nc3)N1CCOC2 |r| Show InChI InChI=1S/C20H26N6O2/c1-20(2)12-28-8-6-26(20)19-15-9-14-11-27-7-5-25(14)18(15)23-17(24-19)13-3-4-16(21)22-10-13/h3-4,10,14H,5-9,11-12H2,1-2H3,(H2,21,22)/t14-/m1/s1	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	409	n/a	n/a	n/a	n/a	n/a	n/a
University of Basel Curated by ChEMBL					Assay Description Inhibition of mTORC2 in human A2058 cells assessed as reduction in PKB phosphorylation at S473 residues incubated for 1 hr by Western blot analysis				J Med Chem 62: 8609-8630 (2019) Article DOI: 10.1021/acs.jmedchem.9b00972 BindingDB Entry DOI: 10.7270/Q2DJ5JW1
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