Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kJ/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
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Target of rapamycin complex subunit LST8 (Homo sapiens) | BDBM36409![]() (2-(4-amino-1-isopropyl-1H-pyrazolo[3,4-d]pyrimidin...) | PDB KEGG UniProtKB/SwissProt DrugBank GoogleScholar AffyNet ![]() | Purchase MCE MMDB PC cid PC sid PDB UniChem Patents Similars | PDB Article PubMed | n/a | n/a | 8 | n/a | n/a | n/a | n/a | n/a | n/a |
China Pharmaceutical University Curated by ChEMBL | Assay Description Inhibition of mTORC1 (unknown origin) | J Med Chem 61: 4656-4687 (2018) Article DOI: 10.1021/acs.jmedchem.7b01019 BindingDB Entry DOI: 10.7270/Q2RR22GW | |||||||||||
More data for this Ligand-Target Pair | ![]() 3D Structure (crystal) |