Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Target of rapamycin complex subunit LST8' and Ligand = 'BDBM50490556'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Target of rapamycin complex subunit LST8 (Homo sapiens)	BDBM50490556 (CHEMBL2338394) Show SMILES [H][C@]12CC[C@]([H])(C[C@H](C1)c1nc3c(cnn3c3[nH]ccc13)-c1ccc(nc1)-c1ncc[nH]1)N2C(=O)c1nnc[nH]1 |r| Show InChI InChI=1S/C26H23N11O/c38-26(23-31-13-32-35-23)36-16-2-3-17(36)10-15(9-16)21-18-5-6-29-24(18)37-25(34-21)19(12-33-37)14-1-4-20(30-11-14)22-27-7-8-28-22/h1,4-8,11-13,15-17,29H,2-3,9-10H2,(H,27,28)(H,31,32,35)/t15-,16-,17+	PDB KEGG UniProtKB/SwissProt DrugBank GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	1	n/a	n/a	n/a	n/a	n/a	n/a
Therachem Research Medilab (India) Pvt. Ltd. Curated by ChEMBL					Assay Description Inhibition of mTORC1 in human PC3 cells assessed as reduction in phosphorylated 4E-BP1Thr37/46 level after 90 mins by immunofluorescence assay				ACS Med Chem Lett 4: 321-2 (2013) Article DOI: 10.1021/ml400056x BindingDB Entry DOI: 10.7270/Q2TM7F1R
					More data for this Ligand-Target Pair