Compile Data Set for Download or QSAR

Found 2 hits Enz. Inhib. hit(s) with Target = 'Telomerase reverse transcriptase' and Ligand = 'BDBM50080851'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Telomerase reverse transcriptase (Homo sapiens (Human))	BDBM50080851 (3-Dimethylamino-N-[6-(3-dimethylamino-propionylami...) Show SMILES CN(C)CCC(=O)Nc1ccc2cc3ccc(NC(=O)CCN(C)C)cc3nc2c1 Show InChI InChI=1S/C23H29N5O2/c1-27(2)11-9-22(29)24-18-7-5-16-13-17-6-8-19(15-21(17)26-20(16)14-18)25-23(30)10-12-28(3)4/h5-8,13-15H,9-12H2,1-4H3,(H,24,29)(H,25,30)	PDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	8.20E+3	n/a	n/a	n/a	n/a	n/a	n/a
Central University of Las Villas Curated by ChEMBL					Assay Description Inhibition of telomerase in human A2780 cells by TRAP assay				Eur J Med Chem 44: 4826-40 (2009) Article DOI: 10.1016/j.ejmech.2009.07.029 BindingDB Entry DOI: 10.7270/Q20R9PHM
					More data for this Ligand-Target Pair
Telomerase reverse transcriptase (Homo sapiens (Human))	BDBM50080851 (3-Dimethylamino-N-[6-(3-dimethylamino-propionylami...) Show SMILES CN(C)CCC(=O)Nc1ccc2cc3ccc(NC(=O)CCN(C)C)cc3nc2c1 Show InChI InChI=1S/C23H29N5O2/c1-27(2)11-9-22(29)24-18-7-5-16-13-17-6-8-19(15-21(17)26-20(16)14-18)25-23(30)10-12-28(3)4/h5-8,13-15H,9-12H2,1-4H3,(H,24,29)(H,25,30)	PDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	8.20E+3	n/a	n/a	n/a	n/a	n/a	n/a
Institute of Cancer Research Curated by ChEMBL					Assay Description Ability to inhibit human telomerase in a modified cell-free TRAP assay using extracts from A2780 cell line				Bioorg Med Chem Lett 9: 2463-8 (1999) BindingDB Entry DOI: 10.7270/Q2H41QN7
					More data for this Ligand-Target Pair