Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Telomerase reverse transcriptase' and Ligand = 'BDBM50104468'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Telomerase reverse transcriptase (Homo sapiens (Human))	BDBM50104468 (CHEMBL313345 | Phosphoric acid 2-chloro-phenyl est...) Show SMILES OP(=O)(OCCCCCCCCCCCCNC(=O)[C@@H](Cc1c[nH]c2ccccc12)NC(=O)[C@H]1CCCN1)Oc1ccccc1Cl Show InChI InChI=1S/C34H48ClN4O6P/c35-28-17-10-12-20-32(28)45-46(42,43)44-23-14-8-6-4-2-1-3-5-7-13-21-37-33(40)31(39-34(41)30-19-15-22-36-30)24-26-25-38-29-18-11-9-16-27(26)29/h9-12,16-18,20,25,30-31,36,38H,1-8,13-15,19,21-24H2,(H,37,40)(H,39,41)(H,42,43)/t30-,31-/m1/s1	PDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	>1.00E+5	n/a	n/a	n/a	n/a	n/a	n/a
Kyushu University Curated by ChEMBL					Assay Description Inhibitory activity against telomerase extracted from HCT 116 cell lines				Bioorg Med Chem Lett 11: 2581-4 (2001) BindingDB Entry DOI: 10.7270/Q2XD10Z2
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