Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Thrombopoietin receptor' and Ligand = 'BDBM50105940'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Thrombopoietin receptor (Homo sapiens (Human))	BDBM50105940 (4-{N'-[1-(3,4-Dimethyl-phenyl)-5-oxo-1,5-dihydro-p...) Show SMILES Cc1ccc(cc1C)-n1[nH]cc(N=Nc2c(O)cc(c3ccccc23)S(O)(=O)=O)c1=O |w:13.14| Show InChI InChI=1S/C21H18N4O5S/c1-12-7-8-14(9-13(12)2)25-21(27)17(11-22-25)23-24-20-16-6-4-3-5-15(16)19(10-18(20)26)31(28,29)30/h3-11,22,26H,1-2H3,(H,28,29,30)	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	n/a	n/a	100	n/a	n/a	n/a	n/a
GlaxoSmithKline Curated by ChEMBL					Assay Description Effective concentration for thrombopoietin luciferase activity was determined in BAF-3 cells				J Med Chem 44: 3730-45 (2001) BindingDB Entry DOI: 10.7270/Q2MP52KF
					More data for this Ligand-Target Pair