Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Thrombopoietin receptor' and Ligand = 'BDBM50105942'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Thrombopoietin receptor (Homo sapiens (Human))	BDBM50105942 (4-{N'-[1-(3-tert-Butyl-phenyl)-3-methyl-5-oxo-1,5-...) Show SMILES Cc1[nH]n(-c2cccc(c2)C(C)(C)C)c(=O)c1N=Nc1c(O)cc(c2ccccc12)S(O)(=O)=O |w:18.20| Show InChI InChI=1S/C24H24N4O5S/c1-14-21(23(30)28(27-14)16-9-7-8-15(12-16)24(2,3)4)25-26-22-18-11-6-5-10-17(18)20(13-19(22)29)34(31,32)33/h5-13,27,29H,1-4H3,(H,31,32,33)	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	n/a	n/a	70	n/a	n/a	n/a	n/a
GlaxoSmithKline Curated by ChEMBL					Assay Description Effective concentration for thrombopoietin luciferase activity was determined in BAF-3 cells				J Med Chem 44: 3730-45 (2001) BindingDB Entry DOI: 10.7270/Q2MP52KF
					More data for this Ligand-Target Pair