Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Thrombopoietin receptor' and Ligand = 'BDBM50105963'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Thrombopoietin receptor (Homo sapiens (Human))	BDBM50105963 (4-{N'-[1-(3,4-Dimethyl-phenyl)-3-methyl-5-oxo-1,5-...) Show SMILES Cc1[nH]n(-c2ccc(C)c(C)c2)c(=O)c1N=Nc1c(O)cc(c2ccccc12)S(O)(=O)=O |w:16.18| Show InChI InChI=1S/C22H20N4O5S/c1-12-8-9-15(10-13(12)2)26-22(28)20(14(3)25-26)23-24-21-17-7-5-4-6-16(17)19(11-18(21)27)32(29,30)31/h4-11,25,27H,1-3H3,(H,29,30,31)	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	n/a	n/a	40	n/a	n/a	n/a	n/a
GlaxoSmithKline Curated by ChEMBL					Assay Description Effective concentration for thrombopoietin luciferase activity was determined in BAF-3 cells				J Med Chem 44: 3730-45 (2001) BindingDB Entry DOI: 10.7270/Q2MP52KF
					More data for this Ligand-Target Pair