Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Thrombospondin-1' and Ligand = 'BDBM50541829'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Thrombospondin-1 (Homo sapiens)	BDBM50541829 (CHEMBL4638959) Show SMILES CC(C)C[C@H](NC(=O)[C@H](CCCCNC(C)=O)NC(=O)[C@H](CO)NC(C)=O)C(N)=O |r| Show InChI InChI=1S/C19H35N5O6/c1-11(2)9-15(17(20)28)24-18(29)14(7-5-6-8-21-12(3)26)23-19(30)16(10-25)22-13(4)27/h11,14-16,25H,5-10H2,1-4H3,(H2,20,28)(H,21,26)(H,22,27)(H,23,30)(H,24,29)/t14-,15-,16-/m0/s1	PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet	KEGG PC cid PC sid UniChem	Article PubMed	n/a	n/a	15	n/a	n/a	n/a	n/a	n/a	n/a
Southern Research Institute Curated by ChEMBL					Assay Description Inhibition of TSP1 in human myeloma cells assessed reduction in TGFbeta activity incubated for 1 hr by ELISA				ACS Med Chem Lett 11: 1130-1136 (2020) Article DOI: 10.1021/acsmedchemlett.9b00540 BindingDB Entry DOI: 10.7270/Q2M330BV
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