Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Thrombospondin-1' and Ligand = 'BDBM50541836'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Thrombospondin-1 (Homo sapiens)	BDBM50541836 (CHEMBL4642780) Show SMILES CC(C)C[C@@H](NC(=O)[C@H](CCCCN)NC(=O)[C@H](CO)NC(C)=O)C(N)=O |r| Show InChI InChI=1S/C17H33N5O5/c1-10(2)8-13(15(19)25)22-16(26)12(6-4-5-7-18)21-17(27)14(9-23)20-11(3)24/h10,12-14,23H,4-9,18H2,1-3H3,(H2,19,25)(H,20,24)(H,21,27)(H,22,26)/t12-,13+,14-/m0/s1	PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	2	n/a	n/a	n/a	n/a	n/a	n/a
Southern Research Institute Curated by ChEMBL					Assay Description Inhibition of TSP1 in human myeloma cells assessed reduction in TGFbeta activity incubated for 1 hr by ELISA				ACS Med Chem Lett 11: 1130-1136 (2020) Article DOI: 10.1021/acsmedchemlett.9b00540 BindingDB Entry DOI: 10.7270/Q2M330BV
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