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Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Thyrotropin receptor' and Ligand = 'BDBM60851'   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kJ/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Thyrotropin receptor


(Homo sapiens (Human))		BDBM60851
PNG
(US9174940, 18)
Show SMILES CC(=O)N1c2ccc(NC(=O)CCc3ccc(Cl)cc3)cc2C(C)(CC1(C)C)c1ccccc1
Show InChI InChI=1S/C29H31ClN2O2/c1-20(33)32-26-16-15-24(31-27(34)17-12-21-10-13-23(30)14-11-21)18-25(26)29(4,19-28(32,2)3)22-8-6-5-7-9-22/h5-11,13-16,18H,12,17,19H2,1-4H3,(H,31,34)
PDB

UniProtKB/SwissProt

antibodypedia
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
US Patent
n/an/a<100n/an/an/an/an/an/a



Merck Sharp & Dohme B.V.

US Patent


Assay Description
Antagonist activity of three test compounds against human TSI at the human TSH receptor was tested in Chinese Hamster Ovary (CHO) cells (cultured 16 ...

US Patent US9174940 (2015)


BindingDB Entry DOI: 10.7270/Q2F18XJC
More data for this
Ligand-Target Pair