Compile Data Set for Download or QSAR

Found 2 hits Enz. Inhib. hit(s) with Target = 'Toll-like receptor 7' and Ligand = 'BDBM254784'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Toll-like receptor 7 (Homo sapiens (Human))	BDBM254784 (US9475775, 51 | US9597333, 51) Show SMILES CCCN(CCC(F)(F)F)C(=O)C1=Cc2ccc(cc2N=C(N)C1)C(=O)Nc1cccc(C)c1 |t:12,21| Show InChI InChI=1S/C25H27F3N4O2/c1-3-10-32(11-9-25(26,27)28)24(34)19-13-17-7-8-18(14-21(17)31-22(29)15-19)23(33)30-20-6-4-5-16(2)12-20/h4-8,12-14H,3,9-11,15H2,1-2H3,(H2,29,31)(H,30,33)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	n/a	n/a	2.20E+4	n/a	n/a	n/a	n/a
Hoffmann-La Roche Inc. US Patent					Assay Description For TLR8 and TLR7 activity testing, HEK-Blue human TLR8 or TLR7 cells (Invivogen, San Diego, Calif., USA) are used, respectively. These cells are des...				US Patent US9597333 (2017) BindingDB Entry DOI: 10.7270/Q2474CXF
					More data for this Ligand-Target Pair
Toll-like receptor 7 (Homo sapiens (Human))	BDBM254784 (US9475775, 51 | US9597333, 51) Show SMILES CCCN(CCC(F)(F)F)C(=O)C1=Cc2ccc(cc2N=C(N)C1)C(=O)Nc1cccc(C)c1 |t:12,21| Show InChI InChI=1S/C25H27F3N4O2/c1-3-10-32(11-9-25(26,27)28)24(34)19-13-17-7-8-18(14-21(17)31-22(29)15-19)23(33)30-20-6-4-5-16(2)12-20/h4-8,12-14H,3,9-11,15H2,1-2H3,(H2,29,31)(H,30,33)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	n/a	n/a	2.20E+4	n/a	n/a	n/a	n/a
Hoffmann-La Roche Inc. US Patent					Assay Description For TLR8 and TLR7 activity testing, HEK-Blue human TLR8 or TLR7 cells (Invivogen, San Diego, Calif., USA) are used, respectively. These cells are des...				US Patent US9475775 (2016) BindingDB Entry DOI: 10.7270/Q2QC02D4
					More data for this Ligand-Target Pair