Compile Data Set for Download or QSAR

Found 2 hits Enz. Inhib. hit(s) with Target = 'Toll-like receptor 7' and Ligand = 'BDBM254786'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Toll-like receptor 7 (Homo sapiens (Human))	BDBM254786 (US9475775, 53 | US9597333, 53) Show SMILES CCCN(CC1CC1)C(=O)C1=Cc2ccc(cc2N=C(N)C1)C(=O)Nc1cccc(C)c1 |t:11,20| Show InChI InChI=1S/C26H30N4O2/c1-3-11-30(16-18-7-8-18)26(32)21-13-19-9-10-20(14-23(19)29-24(27)15-21)25(31)28-22-6-4-5-17(2)12-22/h4-6,9-10,12-14,18H,3,7-8,11,15-16H2,1-2H3,(H2,27,29)(H,28,31)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	n/a	n/a	2.00E+4	n/a	n/a	n/a	n/a
Hoffmann-La Roche Inc. US Patent					Assay Description For TLR8 and TLR7 activity testing, HEK-Blue human TLR8 or TLR7 cells (Invivogen, San Diego, Calif., USA) are used, respectively. These cells are des...				US Patent US9597333 (2017) BindingDB Entry DOI: 10.7270/Q2474CXF
					More data for this Ligand-Target Pair
Toll-like receptor 7 (Homo sapiens (Human))	BDBM254786 (US9475775, 53 | US9597333, 53) Show SMILES CCCN(CC1CC1)C(=O)C1=Cc2ccc(cc2N=C(N)C1)C(=O)Nc1cccc(C)c1 |t:11,20| Show InChI InChI=1S/C26H30N4O2/c1-3-11-30(16-18-7-8-18)26(32)21-13-19-9-10-20(14-23(19)29-24(27)15-21)25(31)28-22-6-4-5-17(2)12-22/h4-6,9-10,12-14,18H,3,7-8,11,15-16H2,1-2H3,(H2,27,29)(H,28,31)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	n/a	n/a	2.00E+4	n/a	n/a	n/a	n/a
Hoffmann-La Roche Inc. US Patent					Assay Description For TLR8 and TLR7 activity testing, HEK-Blue human TLR8 or TLR7 cells (Invivogen, San Diego, Calif., USA) are used, respectively. These cells are des...				US Patent US9475775 (2016) BindingDB Entry DOI: 10.7270/Q2QC02D4
					More data for this Ligand-Target Pair