Compile Data Set for Download or QSAR

Found 2 hits Enz. Inhib. hit(s) with Target = 'Toll-like receptor 7' and Ligand = 'BDBM254789'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Toll-like receptor 7 (Homo sapiens (Human))	BDBM254789 (US9475775, 56 | US9597333, 56) Show SMILES CCCN(CCCOCCCN)C(=O)C1=Cc2ccc(cc2N=C(N)C1)C(=O)Nc1cccc(C)c1 |t:14,23| Show InChI InChI=1S/C28H37N5O3/c1-3-12-33(13-6-15-36-14-5-11-29)28(35)23-17-21-9-10-22(18-25(21)32-26(30)19-23)27(34)31-24-8-4-7-20(2)16-24/h4,7-10,16-18H,3,5-6,11-15,19,29H2,1-2H3,(H2,30,32)(H,31,34)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	n/a	n/a	>1.00E+5	n/a	n/a	n/a	n/a
Hoffmann-La Roche Inc. US Patent					Assay Description For TLR8 and TLR7 activity testing, HEK-Blue human TLR8 or TLR7 cells (Invivogen, San Diego, Calif., USA) are used, respectively. These cells are des...				US Patent US9597333 (2017) BindingDB Entry DOI: 10.7270/Q2474CXF
					More data for this Ligand-Target Pair
Toll-like receptor 7 (Homo sapiens (Human))	BDBM254789 (US9475775, 56 | US9597333, 56) Show SMILES CCCN(CCCOCCCN)C(=O)C1=Cc2ccc(cc2N=C(N)C1)C(=O)Nc1cccc(C)c1 |t:14,23| Show InChI InChI=1S/C28H37N5O3/c1-3-12-33(13-6-15-36-14-5-11-29)28(35)23-17-21-9-10-22(18-25(21)32-26(30)19-23)27(34)31-24-8-4-7-20(2)16-24/h4,7-10,16-18H,3,5-6,11-15,19,29H2,1-2H3,(H2,30,32)(H,31,34)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	n/a	n/a	>1.00E+5	n/a	n/a	n/a	n/a
Hoffmann-La Roche Inc. US Patent					Assay Description For TLR8 and TLR7 activity testing, HEK-Blue human TLR8 or TLR7 cells (Invivogen, San Diego, Calif., USA) are used, respectively. These cells are des...				US Patent US9475775 (2016) BindingDB Entry DOI: 10.7270/Q2QC02D4
					More data for this Ligand-Target Pair