Compile Data Set for Download or QSAR

Found 2 hits Enz. Inhib. hit(s) with Target = 'Toll-like receptor 7' and Ligand = 'BDBM307526'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Toll-like receptor 7 (Homo sapiens (Human))	BDBM307526 ((S)-2-(N-(4-((2-amino-4-(1-hydroxyhexan-3-ylamino)...) Show SMILES CCC[C@@H](CCO)Nc1nc(N)nc(C)c1Cc1ccc(CN(CC(O)=O)C(C)=O)cc1OC |r| Show InChI InChI=1S/C24H35N5O5/c1-5-6-19(9-10-30)27-23-20(15(2)26-24(25)28-23)12-18-8-7-17(11-21(18)34-4)13-29(16(3)31)14-22(32)33/h7-8,11,19,30H,5-6,9-10,12-14H2,1-4H3,(H,32,33)(H3,25,26,27,28)/t19-/m0/s1	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	n/a	n/a	251	n/a	n/a	n/a	n/a
Sumitomo Dainippon Pharma Co., Ltd. US Patent					Assay Description Recombinant human TLR7 was stably expressed in a HEK293 cell line already stably expressing the pNiFty2-SEAP reporter plasmid; integration of the rep...				US Patent US10562861 (2020) BindingDB Entry DOI: 10.7270/Q22F7QTT
					More data for this Ligand-Target Pair
Toll-like receptor 7 (Homo sapiens (Human))	BDBM307526 ((S)-2-(N-(4-((2-amino-4-(1-hydroxyhexan-3-ylamino)...) Show SMILES CCC[C@@H](CCO)Nc1nc(N)nc(C)c1Cc1ccc(CN(CC(O)=O)C(C)=O)cc1OC |r| Show InChI InChI=1S/C24H35N5O5/c1-5-6-19(9-10-30)27-23-20(15(2)26-24(25)28-23)12-18-8-7-17(11-21(18)34-4)13-29(16(3)31)14-22(32)33/h7-8,11,19,30H,5-6,9-10,12-14H2,1-4H3,(H,32,33)(H3,25,26,27,28)/t19-/m0/s1	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	n/a	n/a	6.60E+3	n/a	n/a	n/a	n/a
Sumitomo Dainippon Pharma Co., Ltd. US Patent					Assay Description Recombinant human TLR7 was stably expressed in a HEK293 cell line already stably expressing the pNiFty2-SEAP reporter plasmid; integration of the rep...				US Patent US10150743 (2018) BindingDB Entry DOI: 10.7270/Q2MW2K6N
					More data for this Ligand-Target Pair