Compile Data Set for Download or QSAR

Found 3 hits Enz. Inhib. hit(s) with Target = 'Toll-like receptor 7' and Ligand = 'BDBM307529'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Toll-like receptor 7 (Homo sapiens (Human))	BDBM307529 ((S)-3-((3-(4-((2-amino-4-(1-hydroxyhexan-3-ylamino...) Show SMILES CCC[C@@H](CCO)Nc1nc(N)nc(C)c1Cc1ccc(OCCCN(CC)CC(O)=O)cc1OC |r| Show InChI InChI=1S/C26H41N5O5/c1-5-8-20(11-13-32)29-25-22(18(3)28-26(27)30-25)15-19-9-10-21(16-23(19)35-4)36-14-7-12-31(6-2)17-24(33)34/h9-10,16,20,32H,5-8,11-15,17H2,1-4H3,(H,33,34)(H3,27,28,29,30)/t20-/m0/s1	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	n/a	n/a	6.60E+3	n/a	n/a	n/a	n/a
Sumitomo Dainippon Pharma Co., Ltd. US Patent					Assay Description Recombinant human TLR7 was stably expressed in a HEK293 cell line already stably expressing the pNiFty2-SEAP reporter plasmid; integration of the rep...				US Patent US10150743 (2018) BindingDB Entry DOI: 10.7270/Q2MW2K6N
					More data for this Ligand-Target Pair
Toll-like receptor 7 (Homo sapiens (Human))	BDBM307529 ((S)-3-((3-(4-((2-amino-4-(1-hydroxyhexan-3-ylamino...) Show SMILES CCC[C@@H](CCO)Nc1nc(N)nc(C)c1Cc1ccc(OCCCN(CC)CC(O)=O)cc1OC |r| Show InChI InChI=1S/C26H41N5O5/c1-5-8-20(11-13-32)29-25-22(18(3)28-26(27)30-25)15-19-9-10-21(16-23(19)35-4)36-14-7-12-31(6-2)17-24(33)34/h9-10,16,20,32H,5-8,11-15,17H2,1-4H3,(H,33,34)(H3,27,28,29,30)/t20-/m0/s1	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	n/a	n/a	200	n/a	n/a	n/a	n/a
Sumitomo Dainippon Pharma Co., Ltd. US Patent					Assay Description Recombinant human TLR7 was stably expressed in a HEK293 cell line already stably expressing the pNiFty2-SEAP reporter plasmid; integration of the rep...				US Patent US10562861 (2020) BindingDB Entry DOI: 10.7270/Q22F7QTT
					More data for this Ligand-Target Pair
Toll-like receptor 7 (Homo sapiens (Human))	BDBM307529 ((S)-3-((3-(4-((2-amino-4-(1-hydroxyhexan-3-ylamino...) Show SMILES CCC[C@@H](CCO)Nc1nc(N)nc(C)c1Cc1ccc(OCCCN(CC)CC(O)=O)cc1OC |r| Show InChI InChI=1S/C26H41N5O5/c1-5-8-20(11-13-32)29-25-22(18(3)28-26(27)30-25)15-19-9-10-21(16-23(19)35-4)36-14-7-12-31(6-2)17-24(33)34/h9-10,16,20,32H,5-8,11-15,17H2,1-4H3,(H,33,34)(H3,27,28,29,30)/t20-/m0/s1	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	n/a	n/a	6.70E+3	n/a	n/a	n/a	n/a
Sumitomo Dainippon Pharma Co., Ltd. US Patent					Assay Description Recombinant human TLR7 was stably expressed in a HEK293 cell line already stably expressing the pNiFty2-SEAP reporter plasmid; integration of the rep...				US Patent US10150743 (2018) BindingDB Entry DOI: 10.7270/Q2MW2K6N
					More data for this Ligand-Target Pair