Compile Data Set for Download or QSAR

Found 3 hits Enz. Inhib. hit(s) with Target = 'Toll-like receptor 7' and Ligand = 'BDBM428145'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Toll-like receptor 7 (Homo sapiens (Human))	BDBM428145 (US10544143, Example 581 | US10730877, Example 581 ...) Show SMILES CC(C)c1c([nH]c2cc(C)c(nc12)C1CCN(CC(=O)N(C)C)CC1)-c1cc(C)c2ncnn2c1 Show InChI InChI=1S/C27H35N7O/c1-16(2)23-25(20-11-18(4)27-28-15-29-34(27)13-20)30-21-12-17(3)24(31-26(21)23)19-7-9-33(10-8-19)14-22(35)32(5)6/h11-13,15-16,19,30H,7-10,14H2,1-6H3	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	0.300	n/a	n/a	n/a	n/a	n/a	n/a
Bristol-Myers Squibb Company US Patent					Assay Description HEK-Blue-cells (Invivogen) overexpressing human TLR7, TLR8 or TLR9 receptors were used for screening inhibitors of these receptors using an inducible...				US Patent US10544143 (2020) BindingDB Entry DOI: 10.7270/Q2QF8W80
					More data for this Ligand-Target Pair
Toll-like receptor 7 (Homo sapiens (Human))	BDBM428145 (US10544143, Example 581 | US10730877, Example 581 ...) Show SMILES CC(C)c1c([nH]c2cc(C)c(nc12)C1CCN(CC(=O)N(C)C)CC1)-c1cc(C)c2ncnn2c1 Show InChI InChI=1S/C27H35N7O/c1-16(2)23-25(20-11-18(4)27-28-15-29-34(27)13-20)30-21-12-17(3)24(31-26(21)23)19-7-9-33(10-8-19)14-22(35)32(5)6/h11-13,15-16,19,30H,7-10,14H2,1-6H3	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	0.300	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description HEK-Blue™-cells (Invivogen) overexpressing human TLR7, TLR8 or TLR9 receptors were used for screening inhibitors of these receptors using an inducibl...				Citation and Details BindingDB Entry DOI: 10.7270/Q2S46W4Z
					More data for this Ligand-Target Pair
Toll-like receptor 7 (Homo sapiens (Human))	BDBM428145 (US10544143, Example 581 | US10730877, Example 581 ...) Show SMILES CC(C)c1c([nH]c2cc(C)c(nc12)C1CCN(CC(=O)N(C)C)CC1)-c1cc(C)c2ncnn2c1 Show InChI InChI=1S/C27H35N7O/c1-16(2)23-25(20-11-18(4)27-28-15-29-34(27)13-20)30-21-12-17(3)24(31-26(21)23)19-7-9-33(10-8-19)14-22(35)32(5)6/h11-13,15-16,19,30H,7-10,14H2,1-6H3	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	0.300	n/a	n/a	n/a	n/a	n/a	n/a
Bristol-Myers Squibb Company US Patent					Assay Description HEK-Blue-cells (Invivogen) overexpressing human TLR7, TLR8 or TLR9 receptors were used for screening inhibitors of these receptors using an inducible...				US Patent US10730877 (2020) BindingDB Entry DOI: 10.7270/Q2H41VH3
					More data for this Ligand-Target Pair