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Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Toll-like receptor 7' and Ligand = 'BDBM433565'   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kJ/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Toll-like receptor 7


(Homo sapiens (Human))		BDBM433565
PNG
((S)-3-((3-(4-((2-amino-4-(1-hydroxyhexan-3-ylamino...)
Show SMILES CCC[C@@H](CCO)Nc1nc(N)nc(C)c1Cc1ccc(OCCCN(CC)CCC(O)=O)cc1OC |r|
Show InChI InChI=1S/C27H43N5O5/c1-5-8-21(12-15-33)30-26-23(19(3)29-27(28)31-26)17-20-9-10-22(18-24(20)36-4)37-16-7-13-32(6-2)14-11-25(34)35/h9-10,18,21,33H,5-8,11-17H2,1-4H3,(H,34,35)(H3,28,29,30,31)/t21-/m0/s1
PDB

UniProtKB/SwissProt

antibodypedia
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PC cid
PC sid
UniChem
US Patent
n/an/an/an/a 251n/an/an/an/a



Sumitomo Dainippon Pharma Co., Ltd.

US Patent


Assay Description
Recombinant human TLR7 was stably expressed in a HEK293 cell line already stably expressing the pNiFty2-SEAP reporter plasmid; integration of the rep...

US Patent US10562861 (2020)


BindingDB Entry DOI: 10.7270/Q22F7QTT
More data for this
Ligand-Target Pair