Compile Data Set for Download or QSAR

Found 2 hits Enz. Inhib. hit(s) with Target = 'Toll-like receptor 7' and Ligand = 'BDBM441975'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Toll-like receptor 7 (Homo sapiens (Human))	BDBM441975 (US10660877, Example 6) Show SMILES CC(C)c1c([nH]c2ccc(cc12)C1CCNCC1)-c1ccnc(c1)C(F)(F)F Show InChI InChI=1S/C22H24F3N3/c1-13(2)20-17-11-15(14-5-8-26-9-6-14)3-4-18(17)28-21(20)16-7-10-27-19(12-16)22(23,24)25/h3-4,7,10-14,26,28H,5-6,8-9H2,1-2H3	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	28	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details Article DOI: 10.1021/acsmedchemlett.2c00049 BindingDB Entry DOI: 10.7270/Q2JH3R6P
					More data for this Ligand-Target Pair
Toll-like receptor 7 (Homo sapiens (Human))	BDBM441975 (US10660877, Example 6) Show SMILES CC(C)c1c([nH]c2ccc(cc12)C1CCNCC1)-c1ccnc(c1)C(F)(F)F Show InChI InChI=1S/C22H24F3N3/c1-13(2)20-17-11-15(14-5-8-26-9-6-14)3-4-18(17)28-21(20)16-7-10-27-19(12-16)22(23,24)25/h3-4,7,10-14,26,28H,5-6,8-9H2,1-2H3	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	28.2	n/a	n/a	n/a	n/a	n/a	n/a
Bristol-Myers Squibb Company US Patent					Assay Description HEK-Blue-cells (Invivogen) overexpressing human TLR7, TLR8 or TLR9 receptors were used for screening inhibitors of these receptors using an inducible...				US Patent US10660877 (2020) BindingDB Entry DOI: 10.7270/Q24M97K0
					More data for this Ligand-Target Pair