Compile Data Set for Download or QSAR

Found 2 hits Enz. Inhib. hit(s) with Target = 'Toll-like receptor 7' and Ligand = 'BDBM443891'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Toll-like receptor 7 (Homo sapiens (Human))	BDBM443891 (2-(2-ethyl-6-methylpyridin-4-yl)-3-isopropyl-5-(pi...) Show SMILES CCc1cc(cc(C)n1)-c1[nH]c2ccc(cc2c1C(C)C)C1CCNCC1 Show InChI InChI=1S/C24H31N3/c1-5-20-13-19(12-16(4)26-20)24-23(15(2)3)21-14-18(6-7-22(21)27-24)17-8-10-25-11-9-17/h6-7,12-15,17,25,27H,5,8-11H2,1-4H3	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	57	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details Article DOI: 10.1021/acsmedchemlett.2c00049 BindingDB Entry DOI: 10.7270/Q2JH3R6P
					More data for this Ligand-Target Pair
Toll-like receptor 7 (Homo sapiens (Human))	BDBM443891 (2-(2-ethyl-6-methylpyridin-4-yl)-3-isopropyl-5-(pi...) Show SMILES CCc1cc(cc(C)n1)-c1[nH]c2ccc(cc2c1C(C)C)C1CCNCC1 Show InChI InChI=1S/C24H31N3/c1-5-20-13-19(12-16(4)26-20)24-23(15(2)3)21-14-18(6-7-22(21)27-24)17-8-10-25-11-9-17/h6-7,12-15,17,25,27H,5,8-11H2,1-4H3	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	98.4	n/a	n/a	n/a	n/a	n/a	n/a
Bristol-Myers Squibb Company US Patent					Assay Description HEK-Blue-cells (Invivogen) overexpressing human TLR7, TLR8 or TLR9 receptors were used for screening inhibitors of these receptors using an inducible...				US Patent US10660877 (2020) BindingDB Entry DOI: 10.7270/Q24M97K0
					More data for this Ligand-Target Pair