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Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Toll-like receptor 7' and Ligand = 'BDBM450031'   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kJ/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Toll-like receptor 7


(Homo sapiens (Human))		BDBM450031
PNG
(1-[4-(4-{[6-Amino-2-ethoxy-8-(5-fluoropyridin-3-yl...)
Show SMILES CCOc1nc(N)c2nc(-c3cncc(F)c3)n(Cc3ccc(cc3)C3CCN(CC3)C(=O)CN(C)C)c2n1
Show InChI InChI=1S/C28H33FN8O2/c1-4-39-28-33-25(30)24-27(34-28)37(26(32-24)21-13-22(29)15-31-14-21)16-18-5-7-19(8-6-18)20-9-11-36(12-10-20)23(38)17-35(2)3/h5-8,13-15,20H,4,9-12,16-17H2,1-3H3,(H2,30,33,34)
PDB

UniProtKB/SwissProt

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PC cid
PC sid
UniChem
US Patent
n/an/a 16n/an/an/an/an/an/a



SUMITOMO DAINIPPON PHARMA CO., LTD.

US Patent


Assay Description
As human TLR7 expressing cell line, HEK293 cell line was bought from IMGENEX Corporation (TLR7/NF-ηB/SEAPorter™ HEK293 cell), which is human emb...

US Patent US10703755 (2020)


BindingDB Entry DOI: 10.7270/Q28W3HBW
More data for this
Ligand-Target Pair