Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Toll-like receptor 7' and Ligand = 'BDBM450099'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Toll-like receptor 7 (Homo sapiens (Human))	BDBM450099 (US10703755, Example 280) Show SMILES COc1nc(C)c2nc(-c3cncc(F)c3)n(Cc3ccc(CN4C[C@@H]5C[C@H]4CN5C)cc3F)c2n1 |r| Show InChI InChI=1S/C26H27F2N7O/c1-15-23-25(32-26(30-15)36-3)35(24(31-23)18-7-19(27)10-29-9-18)12-17-5-4-16(6-22(17)28)11-34-14-20-8-21(34)13-33(20)2/h4-7,9-10,20-21H,8,11-14H2,1-3H3/t20-,21-/m0/s1	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	3	n/a	n/a	n/a	n/a	n/a	n/a
SUMITOMO DAINIPPON PHARMA CO., LTD. US Patent					Assay Description As human TLR7 expressing cell line, HEK293 cell line was bought from IMGENEX Corporation (TLR7/NF-ηB/SEAPorter™ HEK293 cell), which is human emb...				US Patent US10703755 (2020) BindingDB Entry DOI: 10.7270/Q28W3HBW
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