Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Toll-like receptor 7' and Ligand = 'BDBM450130'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Toll-like receptor 7 (Homo sapiens (Human))	BDBM450130 (US10703755, Example 313) Show SMILES CCOc1nc(C)c2nc(-c3cncc(F)c3)n(Cc3ccc(CN4CC5CC4CN5C)cc3F)c2n1 Show InChI InChI=1S/C27H29F2N7O/c1-4-37-27-31-16(2)24-26(33-27)36(25(32-24)19-8-20(28)11-30-10-19)13-18-6-5-17(7-23(18)29)12-35-15-21-9-22(35)14-34(21)3/h5-8,10-11,21-22H,4,9,12-15H2,1-3H3	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	8	n/a	n/a	n/a	n/a	n/a	n/a
SUMITOMO DAINIPPON PHARMA CO., LTD. US Patent					Assay Description As human TLR7 expressing cell line, HEK293 cell line was bought from IMGENEX Corporation (TLR7/NF-ηB/SEAPorter™ HEK293 cell), which is human emb...				US Patent US10703755 (2020) BindingDB Entry DOI: 10.7270/Q28W3HBW
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