Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Toll-like receptor 7' and Ligand = 'BDBM450213'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Toll-like receptor 7 (Homo sapiens (Human))	BDBM450213 (US10703755, Example 418) Show SMILES COc1nc(C)c2nc(-c3cncc(F)c3)n(Cc3ccc(O[C@H]4C[C@@H]5CC[C@H](C4)N5C)cc3F)c2n1 |r,THB:31:30:29.24.23:27.26| Show InChI InChI=1S/C27H28F2N6O2/c1-15-24-26(33-27(31-15)36-3)35(25(32-24)17-8-18(28)13-30-12-17)14-16-4-7-21(11-23(16)29)37-22-9-19-5-6-20(10-22)34(19)2/h4,7-8,11-13,19-20,22H,5-6,9-10,14H2,1-3H3/t19-,20+,22-	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	19	n/a	n/a	n/a	n/a	n/a	n/a
SUMITOMO DAINIPPON PHARMA CO., LTD. US Patent					Assay Description As human TLR7 expressing cell line, HEK293 cell line was bought from IMGENEX Corporation (TLR7/NF-ηB/SEAPorter™ HEK293 cell), which is human emb...				US Patent US10703755 (2020) BindingDB Entry DOI: 10.7270/Q28W3HBW
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