BindingDB logo
myBDB logout
Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Toll-like receptor 7' and Ligand = 'BDBM483336'   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kJ/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Toll-like receptor 7


(Homo sapiens (Human))		BDBM483336
PNG
(US10919895, Compound Ib-08)
Show SMILES CCCCOc1nc(N)c2nc(O)n(Cc3ccc(CNCCCOCCOCCOCCCNC(=O)OC(C)(C)C)cn3)c2n1
Show InChI InChI=1S/C31H50N8O7/c1-5-6-15-45-28-37-26(32)25-27(38-28)39(29(40)36-25)22-24-10-9-23(21-35-24)20-33-11-7-13-42-16-18-44-19-17-43-14-8-12-34-30(41)46-31(2,3)4/h9-10,21,33H,5-8,11-20,22H2,1-4H3,(H,34,41)(H,36,40)(H2,32,37,38)
PDB

UniProtKB/SwissProt

antibodypedia
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
US Patent
n/an/an/an/a 47n/an/an/an/a



Bristol-Myers Squibb Company

US Patent


Assay Description
Engineered human embryonic kidney blue cells (HEK-Blue™ TLR cells; Invivogen) possessing a human TLR7-secreted embryonic alkaline phosphatase (SEAP) ...

US Patent US10919895 (2021)


BindingDB Entry DOI: 10.7270/Q2KS6VNZ
More data for this
Ligand-Target Pair