Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Toll-like receptor 7' and Ligand = 'BDBM50236148'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Toll-like receptor 7 (Homo sapiens (Human))	BDBM50236148 (CHEMBL4065927) Show SMILES CCCCNc1nc(N)nc(C)c1CCCn1ccc2ccccc12 Show InChI InChI=1S/C20H27N5/c1-3-4-12-22-19-17(15(2)23-20(21)24-19)9-7-13-25-14-11-16-8-5-6-10-18(16)25/h5-6,8,10-11,14H,3-4,7,9,12-13H2,1-2H3,(H3,21,22,23,24)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	n/a	n/a	n/a	n/a	140	n/a	n/a	n/a	n/a
University of Minnesota Curated by ChEMBL					Assay Description Agonist activity at human TLR7 expressed in HEK293 cells co-expressing secreted alkaline phosphatase assessed as induction of NF-kappaB/AP-1 promoter...				J Med Chem 60: 2084-2098 (2017) Article DOI: 10.1021/acs.jmedchem.6b01860 BindingDB Entry DOI: 10.7270/Q27083QG
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