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Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Toll-like receptor 7' and Ligand = 'BDBM50320074'   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kJ/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Toll-like receptor 7


(Homo sapiens (Human))		BDBM50320074
PNG
(1-Benzyl-2-hexyl-1H-imidazo[4,5-c]quinolin-4-amine...)
Show SMILES CCCCCCc1nc2c(N)nc3ccccc3c2n1Cc1ccccc1
Show InChI InChI=1S/C23H26N4/c1-2-3-4-8-15-20-26-21-22(27(20)16-17-11-6-5-7-12-17)18-13-9-10-14-19(18)25-23(21)24/h5-7,9-14H,2-4,8,15-16H2,1H3,(H2,24,25)
PDB

UniProtKB/SwissProt

antibodypedia
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PC cid
PC sid
UniChem

Similars
Article
PubMed
n/an/an/an/a 479n/an/an/an/a



University of Kansas

Curated by ChEMBL


Assay Description
Agonist activity at human TLR7 expressed in NFkappaB-stimulated HEK293 cells assessed as induction of secreted alkaline phosphatase expression by rep...

J Med Chem 53: 4450-65 (2010)


Article DOI: 10.1021/jm100358c
BindingDB Entry DOI: 10.7270/Q2Q52PS6
More data for this
Ligand-Target Pair