Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Toll-like receptor 7' and Ligand = 'BDBM50514146'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Toll-like receptor 7 (Homo sapiens (Human))	BDBM50514146 (CHEMBL4460132) Show SMILES Fc1cccnc1C(=O)Nc1ccc(Oc2cc(cc(c2)C(F)(F)F)C(F)(F)F)cc1 Show InChI InChI=1S/C20H11F7N2O2/c21-16-2-1-7-28-17(16)18(30)29-13-3-5-14(6-4-13)31-15-9-11(19(22,23)24)8-12(10-15)20(25,26)27/h1-10H,(H,29,30)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	>5.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
University of Colorado Boulder Curated by ChEMBL					Assay Description Inhibition of human TLR7 expressed in HEK293 cells assessed as reduction in R848-induced NFkappaB production incubated for 16 hrs by quanti-blue SEAP...				J Med Chem 62: 10221-10244 (2019) Article DOI: 10.1021/acs.jmedchem.9b01201 BindingDB Entry DOI: 10.7270/Q2BP064W
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