Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Toll-like receptor 8' and Ligand = 'BDBM50236173'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Toll-like receptor 8 (Homo sapiens (Human))	BDBM50236173 (CHEMBL4103484) Show SMILES CCCCNc1nc(N)nc(C)c1C#C[Si](C)(C)C Show InChI InChI=1S/C14H24N4Si/c1-6-7-9-16-13-12(8-10-19(3,4)5)11(2)17-14(15)18-13/h6-7,9H2,1-5H3,(H3,15,16,17,18)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	9.24E+3	n/a	n/a	n/a	n/a
University of Minnesota Curated by ChEMBL					Assay Description Agonist activity at human TLR8 expressed in HEK293 cells co-expressing secreted alkaline phosphatase assessed as induction of NF-kappaB/AP-1 promoter...				J Med Chem 60: 2084-2098 (2017) Article DOI: 10.1021/acs.jmedchem.6b01860 BindingDB Entry DOI: 10.7270/Q27083QG
					More data for this Ligand-Target Pair