Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Toll-like receptor 8' and Ligand = 'BDBM50514796'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Toll-like receptor 8 (Homo sapiens (Human))	BDBM50514796 (CHEMBL4535822) Show SMILES CCSc1nnc(CCCO)n1-c1ccc(Cl)cc1Cl |(16.41,-8.45,;14.94,-7.99,;13.8,-9.02,;12.34,-8.56,;11.85,-7.1,;10.31,-7.11,;9.84,-8.57,;8.38,-9.06,;7.23,-8.04,;7.54,-6.53,;6.39,-5.51,;11.1,-9.47,;11.11,-11.01,;12.44,-11.77,;12.45,-13.31,;11.12,-14.09,;11.13,-15.63,;9.79,-13.33,;9.78,-11.79,;8.44,-11.03,)| Show InChI InChI=1S/C13H15Cl2N3OS/c1-2-20-13-17-16-12(4-3-7-19)18(13)11-6-5-9(14)8-10(11)15/h5-6,8,19H,2-4,7H2,1H3	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	390	n/a	n/a	n/a	n/a	n/a	n/a
The University of Tokyo Curated by ChEMBL					Assay Description Inhibition of human TLR8 expressed in HEK-Blue cells assessed as inhibition of R848-induced NF-kappaB activation measured after 24 hrs by quanti-blue...				J Med Chem 63: 4117-4132 (2020) Article DOI: 10.1021/acs.jmedchem.9b02128 BindingDB Entry DOI: 10.7270/Q2NV9NMG
					More data for this Ligand-Target Pair