Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Toll-like receptor 8' and Ligand = 'BDBM50514798'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Toll-like receptor 8 (Homo sapiens (Human))	BDBM50514798 (CHEMBL4554556) Show SMILES CSc1nnc(O)n1-c1ccc(Cl)cc1Cl |(9.88,-10.43,;8.76,-11.48,;7.28,-11.04,;6.78,-9.58,;5.24,-9.61,;4.79,-11.09,;3.34,-11.59,;6.06,-11.97,;6.09,-13.51,;7.43,-14.25,;7.47,-15.79,;6.15,-16.59,;6.18,-18.13,;4.8,-15.84,;4.77,-14.3,;3.42,-13.56,)| Show InChI InChI=1S/C9H7Cl2N3OS/c1-16-9-13-12-8(15)14(9)7-3-2-5(10)4-6(7)11/h2-4H,1H3,(H,12,15)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	9.00E+3	n/a	n/a	n/a	n/a	n/a	n/a
The University of Tokyo Curated by ChEMBL					Assay Description Inhibition of human TLR8 expressed in HEK-Blue cells assessed as inhibition of R848-induced NF-kappaB activation measured after 24 hrs by quanti-blue...				J Med Chem 63: 4117-4132 (2020) Article DOI: 10.1021/acs.jmedchem.9b02128 BindingDB Entry DOI: 10.7270/Q2NV9NMG
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