Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Toll-like receptor 8' and Ligand = 'BDBM50514799'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Toll-like receptor 8 (Homo sapiens (Human))	BDBM50514799 (CHEMBL4445770) Show SMILES CSc1nnc(CCO)n1-c1ccc(Cl)cc1Cl |(15.33,-12.38,;14.19,-13.42,;12.72,-12.95,;12.24,-11.48,;10.7,-11.49,;10.23,-12.96,;8.77,-13.44,;7.62,-12.42,;6.16,-12.9,;11.48,-13.86,;11.49,-15.4,;12.82,-16.16,;12.83,-17.7,;11.5,-18.48,;11.51,-20.02,;10.16,-17.71,;10.16,-16.17,;8.82,-15.41,)| Show InChI InChI=1S/C11H11Cl2N3OS/c1-18-11-15-14-10(4-5-17)16(11)9-3-2-7(12)6-8(9)13/h2-3,6,17H,4-5H2,1H3	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	590	n/a	n/a	n/a	n/a	n/a	n/a
The University of Tokyo Curated by ChEMBL					Assay Description Inhibition of human TLR8 expressed in HEK-Blue cells assessed as inhibition of R848-induced NF-kappaB activation measured after 24 hrs by quanti-blue...				J Med Chem 63: 4117-4132 (2020) Article DOI: 10.1021/acs.jmedchem.9b02128 BindingDB Entry DOI: 10.7270/Q2NV9NMG
					More data for this Ligand-Target Pair