Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Toll-like receptor 8' and Ligand = 'BDBM50514813'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Toll-like receptor 8 (Homo sapiens (Human))	BDBM50514813 (CHEMBL4471285) Show SMILES CSc1nnc(CCCO)n1-c1cccc(Cl)c1 Show InChI InChI=1S/C12H14ClN3OS/c1-18-12-15-14-11(6-3-7-17)16(12)10-5-2-4-9(13)8-10/h2,4-5,8,17H,3,6-7H2,1H3	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	350	n/a	n/a	n/a	n/a	n/a	n/a
The University of Tokyo Curated by ChEMBL					Assay Description Inhibition of human TLR8 expressed in HEK-Blue cells assessed as inhibition of R848-induced NF-kappaB activation measured after 24 hrs by quanti-blue...				J Med Chem 63: 4117-4132 (2020) Article DOI: 10.1021/acs.jmedchem.9b02128 BindingDB Entry DOI: 10.7270/Q2NV9NMG
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