Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Toll-like receptor 8' and Ligand = 'BDBM50514814'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Toll-like receptor 8 (Homo sapiens (Human))	BDBM50514814 (CHEMBL4437700) Show SMILES CSc1nnc(CCCO)n1-c1c(Cl)cc(Cl)cc1Cl |(25.82,-26.98,;25.2,-28.39,;26.1,-29.63,;27.64,-29.63,;28.12,-31.1,;26.87,-32,;26.87,-33.54,;28.21,-34.31,;29.54,-33.54,;30.87,-34.31,;25.63,-31.1,;24.16,-31.57,;23.02,-30.54,;23.34,-29.04,;21.55,-31.02,;21.23,-32.53,;19.77,-33,;22.38,-33.56,;23.84,-33.08,;24.99,-34.11,)| Show InChI InChI=1S/C12H12Cl3N3OS/c1-20-12-17-16-10(3-2-4-19)18(12)11-8(14)5-7(13)6-9(11)15/h5-6,19H,2-4H2,1H3	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	2.81E+3	n/a	n/a	n/a	n/a	n/a	n/a
The University of Tokyo Curated by ChEMBL					Assay Description Inhibition of human TLR8 expressed in HEK-Blue cells assessed as inhibition of R848-induced NF-kappaB activation measured after 24 hrs by quanti-blue...				J Med Chem 63: 4117-4132 (2020) Article DOI: 10.1021/acs.jmedchem.9b02128 BindingDB Entry DOI: 10.7270/Q2NV9NMG
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