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Found 1 hit Enz. Inhib. hit(s) with Target = 'Toll-like receptor 9' and Ligand = 'BDBM50467770'   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kJ/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Toll-like receptor 9


(Homo sapiens (Human))		BDBM50467770
PNG
(CHEMBL4279467)
Show SMILES COc1cc2c(nc(nc2cc1OCCCN1CCCC1)N(C)C)N1CCNCC1
Show InChI InChI=1S/C22H34N6O2/c1-26(2)22-24-18-16-20(30-14-6-11-27-9-4-5-10-27)19(29-3)15-17(18)21(25-22)28-12-7-23-8-13-28/h15-16,23H,4-14H2,1-3H3
PDB

UniProtKB/SwissProt

antibodypedia
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
Article
PubMed
n/an/a 20n/an/an/an/an/an/a



CSIR-Indian Institute of Chemical Biology

Curated by ChEMBL


Assay Description
Antagonist activity at human TLR9 expressed in HEK-Blue cells assessed as reduction in CpGB-induced NF-kappaB levels after 24 hrs by spectrophotometr...

Eur J Med Chem 159: 187-205 (2018)


Article DOI: 10.1016/j.ejmech.2018.09.058
BindingDB Entry DOI: 10.7270/Q2C2504D
More data for this
Ligand-Target Pair