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Found 1 hit Enz. Inhib. hit(s) with Target = 'Toll-like receptor 9' and Ligand = 'BDBM50467773'   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kJ/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Toll-like receptor 9


(Homo sapiens (Human))		BDBM50467773
PNG
(CHEMBL4282131)
Show SMILES COc1cc2c(nc(nc2cc1OCCCN1CCCC1)N1CCN(C)CC1)N1CCN(CC1)C1CCCC1
Show InChI InChI=1S/C30H47N7O2/c1-33-13-15-37(16-14-33)30-31-26-23-28(39-21-7-12-34-10-5-6-11-34)27(38-2)22-25(26)29(32-30)36-19-17-35(18-20-36)24-8-3-4-9-24/h22-24H,3-21H2,1-2H3
PDB

UniProtKB/SwissProt

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PC cid
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Article
PubMed
n/an/a 20n/an/an/an/an/an/a



CSIR-Indian Institute of Chemical Biology

Curated by ChEMBL


Assay Description
Antagonist activity at human TLR9 expressed in HEK-Blue cells assessed as reduction in CpGB-induced NF-kappaB levels after 24 hrs by spectrophotometr...

Eur J Med Chem 159: 187-205 (2018)


Article DOI: 10.1016/j.ejmech.2018.09.058
BindingDB Entry DOI: 10.7270/Q2C2504D
More data for this
Ligand-Target Pair