BindingDB logo
myBDB logout
Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Toxin ParE' and Ligand = 'BDBM50047287'   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kJ/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Toxin ParE


(Escherichia coli)		BDBM50047287
PNG
(CHEMBL3314574)
Show SMILES CO[C@H]1CN(CC[C@H]1NC(=O)c1[nH]c(C)c(Cl)c1Cl)c1nc(C(=O)NN2CCOCC2)c(s1)C(O)=O |r|
Show InChI InChI=1S/C21H26Cl2N6O6S/c1-10-13(22)14(23)15(24-10)18(30)25-11-3-4-28(9-12(11)34-2)21-26-16(17(36-21)20(32)33)19(31)27-29-5-7-35-8-6-29/h11-12,24H,3-9H2,1-2H3,(H,25,30)(H,27,31)(H,32,33)/t11-,12+/m1/s1
UniProtKB/SwissProt

GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars
Article
PubMed
n/an/a 110n/an/an/an/an/an/a



AstraZeneca

Curated by ChEMBL


Assay Description
Inhibition of ATPase activity of Escherichia coli ParE

J Med Chem 57: 6060-82 (2014)


Article DOI: 10.1021/jm500462x
BindingDB Entry DOI: 10.7270/Q24J0GR1
More data for this
Ligand-Target Pair