BindingDB logo
myBDB logout
Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Transcription factor 4' and Ligand = 'BDBM50500849'   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kJ/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Transcription factor 4


(Homo sapiens)		BDBM50500849
PNG
(CHEMBL3780110)
Show SMILES CO[C@@H]1[C@@H](C)OC(NC2=CC(=O)c3c(O)c4C(=O)[C@]5(OC)[C@H](O)Cc6cc(C)c(C(=O)OC)c(O)c6[C@@]5(O)C(=O)c4cc3C2=O)[C@@H](OC)[C@H]1O |r,t:8|
Show InChI InChI=1S/C34H35NO15/c1-11-7-13-8-18(37)34(49-6)30(43)21-15(29(42)33(34,45)22(13)25(40)19(11)32(44)48-5)9-14-20(24(21)39)17(36)10-16(23(14)38)35-31-28(47-4)26(41)27(46-3)12(2)50-31/h7,9-10,12,18,26-28,31,35,37,39-41,45H,8H2,1-6H3/t12-,18-,26+,27-,28+,31?,33-,34-/m1/s1
PDB

UniProtKB/SwissProt

GoogleScholar
AffyNet 
Purchase

PC cid
PC sid
UniChem
Article
PubMed
n/an/a 640n/an/an/an/an/an/a



King Saud University

Curated by ChEMBL


Assay Description
Inhibition of human GST tagged Tcf4/beta catenin interaction after 2 hrs using fluorescent AP Attophos substrate by ELISA analysis

Bioorg Med Chem Lett 26: 1664-70 (2016)


Article DOI: 10.1016/j.bmcl.2016.02.064
BindingDB Entry DOI: 10.7270/Q25H7K8M
More data for this
Ligand-Target Pair