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Compile Data Set for Download or QSAR

Found 2 hits Enz. Inhib. hit(s) with Target = 'Transcription factor SOX-18' and Ligand = 'BDBM223293'   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kJ/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Transcription factor SOX-18


(Human)
BDBM223293
PNG
(Sm4 | US20240002326, Compound Sm4)
Show SMILES OC(=O)c1c(O)cccc1CCc1ccc2ccccc2c1
Show InChI InChI=1S/C19H16O3/c20-17-7-3-6-15(18(17)19(21)22)11-9-13-8-10-14-4-1-2-5-16(14)12-13/h1-8,10,12,20H,9,11H2,(H,21,22)
PDB

UniProtKB/SwissProt

GoogleScholar
AffyNet 
Purchase

MCE
PC cid
PC sid
UniChem
n/an/a 9.75E+4n/an/an/an/an/an/a


TBA



Citation and Details
More data for this
Ligand-Target Pair
Transcription factor SOX-18


(Mus musculus (Mouse))
BDBM223293
PNG
(Sm4 | US20240002326, Compound Sm4)
Show SMILES OC(=O)c1c(O)cccc1CCc1ccc2ccccc2c1
Show InChI InChI=1S/C19H16O3/c20-17-7-3-6-15(18(17)19(21)22)11-9-13-8-10-14-4-1-2-5-16(14)12-13/h1-8,10,12,20H,9,11H2,(H,21,22)
PDB

UniProtKB/SwissProt

GoogleScholar
AffyNet 
Purchase

MCE
PC cid
PC sid
UniChem
Article
PubMed
n/an/a 9.75E+4n/an/an/an/a7.537



The University of Queensland



Assay Description
The DNA-binding competition assay was performed in 25 μL, in black 384-well plates, using either 30 mM HEPES (N-2-Hydroxyethylpiperazine-N'-2-Etha...


Cell Chem Biol 24: 346-359 (2017)


Article DOI: 10.1016/j.chembiol.2017.01.003
BindingDB Entry DOI: 10.7270/Q2MP5252
More data for this
Ligand-Target Pair