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Found 1 hit Enz. Inhib. hit(s) with Target = 'Transcription initiation factor TFIID subunit 1' and Ligand = 'BDBM50269704'   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kJ/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Transcription initiation factor TFIID subunit 1


(Homo sapiens (Human))		BDBM50269704
PNG
(CHEMBL4061800)
Show SMILES CC(N1CCC(CC1)N(C)C(=O)c1cn(C)c(=O)c2[nH]ccc12)c1ccccc1
Show InChI InChI=1S/C23H28N4O2/c1-16(17-7-5-4-6-8-17)27-13-10-18(11-14-27)26(3)22(28)20-15-25(2)23(29)21-19(20)9-12-24-21/h4-9,12,15-16,18,24H,10-11,13-14H2,1-3H3
PDB

KEGG

UniProtKB/SwissProt

GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
Article
PubMed
n/an/a 3.60E+3n/an/an/an/an/an/a



Genentech Inc., 1 DNA Way, South San Francisco, California 94080, United States.

Curated by ChEMBL


Assay Description
Inhibition of recombinant human N-terminal His6-FLAG-tagged TAF1 bromodomain 2 (unknown origin) expressed in Rosetta2 (DE3) pLysS cells after 60 mins...

ACS Med Chem Lett 8: 737-741 (2017)


Article DOI: 10.1021/acsmedchemlett.7b00132
BindingDB Entry DOI: 10.7270/Q2862JXN
More data for this
Ligand-Target Pair