Compile Data Set for Download or QSAR

Found 3 hits Enz. Inhib. hit(s) with Target = 'Transcriptional activator protein LasR' and Ligand = 'BDBM50248862'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Transcriptional activator protein LasR (Pseudomonas aeruginosa)	BDBM50248862 (CHEMBL473592 | N-(3-oxo-3-phenylpropanoyl)-L-homos...) Show SMILES O=C(CC(=O)N[C@H]1CCOC1=O)Cc1ccccc1 |r| Show InChI InChI=1S/C14H15NO4/c16-11(8-10-4-2-1-3-5-10)9-13(17)15-12-6-7-19-14(12)18/h1-5,12H,6-9H2,(H,15,17)/t12-/m0/s1	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	CHEMBL KEGG PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	5.36E+4	n/a	n/a	n/a	n/a	n/a	n/a
Universidad de Cartagena-Facultad de Ciencias Exactas y Curated by ChEMBL					Assay Description Inhibition of Pseudomonas aeruginosa LasR				Eur J Med Chem 45: 608-15 (2010) Article DOI: 10.1016/j.ejmech.2009.11.004 BindingDB Entry DOI: 10.7270/Q2ZC83SP
					More data for this Ligand-Target Pair
Transcriptional activator protein LasR (Pseudomonas aeruginosa)	BDBM50248862 (CHEMBL473592 | N-(3-oxo-3-phenylpropanoyl)-L-homos...) Show SMILES O=C(CC(=O)N[C@H]1CCOC1=O)Cc1ccccc1 |r| Show InChI InChI=1S/C14H15NO4/c16-11(8-10-4-2-1-3-5-10)9-13(17)15-12-6-7-19-14(12)18/h1-5,12H,6-9H2,(H,15,17)/t12-/m0/s1	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	CHEMBL KEGG PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	7.30E+4	n/a	n/a	n/a	n/a	n/a	n/a
Larkin University Curated by ChEMBL					Assay Description Inhibition of LasR in Pseudomonas aeruginosa PAO-JP2 harboring plasI-LVAgfp incubated for 6 hrs by fluorescence method				Bioorg Med Chem 28: (2020) Article DOI: 10.1016/j.bmc.2019.115282 BindingDB Entry DOI: 10.7270/Q2PN992D
					More data for this Ligand-Target Pair
Transcriptional activator protein LasR (Pseudomonas aeruginosa)	BDBM50248862 (CHEMBL473592 | N-(3-oxo-3-phenylpropanoyl)-L-homos...) Show SMILES O=C(CC(=O)N[C@H]1CCOC1=O)Cc1ccccc1 |r| Show InChI InChI=1S/C14H15NO4/c16-11(8-10-4-2-1-3-5-10)9-13(17)15-12-6-7-19-14(12)18/h1-5,12H,6-9H2,(H,15,17)/t12-/m0/s1	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	CHEMBL KEGG PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	n/a	n/a	540	n/a	n/a	n/a	n/a
The Scripps Research Institute Curated by ChEMBL					Assay Description Agonist activity at Pseudomonas aeruginosa LasR receptor expressed in Escherichia coli in absence of natural autoinducer				J Med Chem 53: 7467-89 (2010) Article DOI: 10.1021/jm901742e BindingDB Entry DOI: 10.7270/Q2S75GPT
					More data for this Ligand-Target Pair