Compile Data Set for Download or QSAR

Found 2 hits Enz. Inhib. hit(s) with Target = 'Transient receptor potential cation channel subfamily A member 1' and Ligand = 'BDBM50390471'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Transient receptor potential cation channel subfamily A member 1 (Homo sapiens (Human))	BDBM50390471 (CHEMBL2071504) Show SMILES CC(C)C(NC(=O)c1ccc(Cl)cc1Cl)C(=O)c1ccc(cc1)C#N Show InChI InChI=1S/C19H16Cl2N2O2/c1-11(2)17(18(24)13-5-3-12(10-22)4-6-13)23-19(25)15-8-7-14(20)9-16(15)21/h3-9,11,17H,1-2H3,(H,23,25)	PDB KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	2.51E+3	n/a	n/a	n/a	n/a	n/a	n/a
AstraZeneca Curated by ChEMBL					Assay Description Antagonist activity at human TRPA1 expressed in HEK293 cells assessed as inhibition of Zn2+-induced intracellular calcium flux by FLIPR assay				Bioorg Med Chem Lett 22: 5485-92 (2012) Article DOI: 10.1016/j.bmcl.2012.07.032 BindingDB Entry DOI: 10.7270/Q2RR20B8
					More data for this Ligand-Target Pair
Transient receptor potential cation channel subfamily A member 1 (Homo sapiens (Human))	BDBM50390471 (CHEMBL2071504) Show SMILES CC(C)C(NC(=O)c1ccc(Cl)cc1Cl)C(=O)c1ccc(cc1)C#N Show InChI InChI=1S/C19H16Cl2N2O2/c1-11(2)17(18(24)13-5-3-12(10-22)4-6-13)23-19(25)15-8-7-14(20)9-16(15)21/h3-9,11,17H,1-2H3,(H,23,25)	PDB KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	5.01E+3	n/a	n/a	n/a	n/a	n/a	n/a
AstraZeneca Curated by ChEMBL					Assay Description Antagonist activity at human TRPA1 expressed in HEK293 cells assessed as inhibition of Ca2+-induced intracellular calcium flux by FLIPR assay				Bioorg Med Chem Lett 22: 5485-92 (2012) Article DOI: 10.1016/j.bmcl.2012.07.032 BindingDB Entry DOI: 10.7270/Q2RR20B8
					More data for this Ligand-Target Pair