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Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Transient receptor potential cation channel subfamily M member 8' and Ligand = 'BDBM151698'   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kJ/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Transient receptor potential cation channel subfamily M member 8


(Homo sapiens (Human))
BDBM151698
PNG
(US8987445, 133)
Show SMILES Cc1cc2cccc(Cl)c2nc1N(Cc1ccc(OC(F)(F)F)cc1)S(=O)(=O)c1ccc(cc1)C(O)=O
Show InChI InChI=1S/C25H18ClF3N2O5S/c1-15-13-18-3-2-4-21(26)22(18)30-23(15)31(14-16-5-9-19(10-6-16)36-25(27,28)29)37(34,35)20-11-7-17(8-12-20)24(32)33/h2-13H,14H2,1H3,(H,32,33)
PDB

KEGG

UniProtKB/SwissProt

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PC cid
PC sid
UniChem

Similars

US Patent
n/an/a 4.30n/an/an/an/an/a37



Mitsubishi Tanabe Pharma Corporation

US Patent


Assay Description
The functional activity of compounds was determined by measuring changes in intracellular calcium concentration using a Ca2+ sensitive fluorescent dy...


US Patent US8987445 (2015)


BindingDB Entry DOI: 10.7270/Q2BZ64R5
More data for this
Ligand-Target Pair