Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Transient receptor potential cation channel subfamily M member 8' and Ligand = 'BDBM151716'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Transient receptor potential cation channel subfamily M member 8 (Homo sapiens (Human))	BDBM151716 (US8987445, 151) Show SMILES OC(=O)c1ccc(cc1)S(=O)(=O)N(Cc1ccc(OC(F)(F)F)cn1)c1ncc2ccccc2c1C1CC1 Show InChI InChI=1S/C26H20F3N3O5S/c27-26(28,29)37-20-10-9-19(30-14-20)15-32(38(35,36)21-11-7-17(8-12-21)25(33)34)24-23(16-5-6-16)22-4-2-1-3-18(22)13-31-24/h1-4,7-14,16H,5-6,15H2,(H,33,34)	PDB KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	2.20	n/a	n/a	n/a	n/a	n/a	37
Mitsubishi Tanabe Pharma Corporation US Patent					Assay Description The functional activity of compounds was determined by measuring changes in intracellular calcium concentration using a Ca2+ sensitive fluorescent dy...				US Patent US8987445 (2015) BindingDB Entry DOI: 10.7270/Q2BZ64R5
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