Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Transient receptor potential cation channel subfamily M member 8' and Ligand = 'BDBM256280'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Transient receptor potential cation channel subfamily M member 8 (Homo sapiens (Human))	BDBM256280 (US9487488, 4) Show SMILES FC(F)(F)Oc1ccc(CN(c2ncc3ccccc3c2C2CC2)S(=O)(=O)c2ccc(cn2)-n2nn[nH]c2=O)cc1 Show InChI InChI=1S/C26H20F3N7O4S/c27-26(28,29)40-20-10-5-16(6-11-20)15-35(24-23(17-7-8-17)21-4-2-1-3-18(21)13-31-24)41(38,39)22-12-9-19(14-30-22)36-25(37)32-33-34-36/h1-6,9-14,17H,7-8,15H2,(H,32,34,37)	PDB KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	1.10	n/a	n/a	n/a	n/a	n/a	37
MITSUBISHI TANABE PHARMA CORPORATION US Patent					Assay Description The functional activity of a test compound was determined by measuring change in intracellular calcium concentration using a calcium sensitive fluore...				US Patent US9487488 (2016) BindingDB Entry DOI: 10.7270/Q2MG7NGT
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